Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.(Microbial infection) Acts as a receptor for adenovirus subgroup B.

T-lymphocyte activation antigen CD86 (Activation B7-2 antigen) (B70) (BU63) (CTLA-4 counter-receptor B7.2) (FUN-1) (CD antigen CD86) CD86 CD28LG2

Human, Mouse

WB,IHC,IF,ICC

WB 1:500-1:2000
IHC 1:50-1:500
IF 1:50-1:500
ICC 1:50-1:500

38kD; 38kDa(Calculated).

CD86 CD28LG2

p42081

https://www.uniprot.org/uniprotkb/p42081

Rabbit

Polyclonal

Rabbit IgG

CD86 Antibody detects endogenous levels of total CD86.

Transmembrane

Adaptive immunity #B-cell activation

PBS,pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Store at -20 °C. Stable for 12 months from date of receipt.

AB_3712426