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The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes . Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion . Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum . Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (By similarity). Required to modulate the compacted morphology of the Golgi . Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment (By similarity).
Q9H0U4
81876
Ras-related protein Rab-1B, RAB1B
Human,Mouse,Rat
WB,FC
WB 1:4000FC 1:25
23 kD
Mouse
monoclonal
IgG1,k
This antibody is purified through a proteinG column.
PBS (pH7.4) with 0.09% (W/V) sodium azide.
Store at -20°C. Stable for 12 months from date of receipt.Do not aliquot the antibody.Avoid freeze / thaw cycle.
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
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订购专线：4006-123-828
销售电话：13916964679（微信同号）
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程经理：手机18616261485（微信同号）
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徐经理：手机15618191473（微信同号）
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