Antagonizes the binding of 2-5A (5\\\\\\'-phosphorylated 2\\\\\\',5\\\\\\'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.

ATP-binding cassette sub-family E member 1 (EC 3.6.5.-) (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40

Human

WB,IHC,ELISA

WB 1:200-1:1000
IHC 1:20-1:200
ELISA 1:5000-1:20000

67.314 kDa ;

ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40

p61221

https://www.uniprot.org/uniprotkb/p61221

Recombinant Human ATP-binding cassette sub-family E member 1 protein (320-599AA)

Rabbit

Polyclonal

IgG

Cancer; Immunology; Metabolism; Signal transduction

>95%, Antigen Affinity Purified

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20°C. Do not aliquot the antibody