Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed: 9299485, PubMed: 9153233, PubMed: 15194431). Competes with bile acid CoA: amino acid N-acyltransferase (BAAT) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (C2 to C20) (PubMed: 9299485, PubMed: 9153233). Inactive towards substrates with more than C20 aliphatic chains (PubMed: 9153233). Involved in the metabolic regulation of peroxisome proliferation (PubMed: 15194431).

Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.1) (EC 3.1.2.11) (EC 3.1.2.2) (EC 3.1.2.3) (EC 3.1.2.5) (Choloyl-coenzyme A thioesterase) (EC 3.1.2.27) (HIV-Nef-associated acyl-CoA thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1) (Thioesterase II) (hACTE-III) (hACTEIII) (hTE) ACOT8 ACTEIII PTE1

Human

IHC,ELISA

IHC 1:20-1:200
ELISA 1:5000-1:20000

35.914 kDa ;

ACOT8 ACTEIII PTE1

o14734

https://www.uniprot.org/uniprotkb/o14734

Recombinant Human Acyl-coenzyme A thioesterase 8 protein (1-200AA)

Rabbit

Polyclonal

IgG

Cancer; Cardiovascular; Tags Cell Markers; Immunology; Metabolism; Signal transduction

>95%, Antigen Affinity Purified

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Store at -20°C. Do not aliquot the antibody