Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.

Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36) VPS36 C13orf9 EAP45 CGI-145

Human

IHC,ELISA

IHC 1:20-1:200
ELISA 1:5000-1:20000

43.817 kDa ;

VPS36 C13orf9 EAP45 CGI-145

q86vn1

https://www.uniprot.org/uniprotkb/q86vn1

Peptide sequence from Human Vacuolar protein-sorting-associated protein 36 protein (87-105AA)

Rabbit

Polyclonal

IgG

Cell biology; Signal transduction

>95%, Antigen Affinity Purified

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Store at -20°C. Do not aliquot the antibody