May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Immunoglobulin mu Fc receptor (IgM FcR) (Fas apoptotic inhibitory molecule 3) (FAIM3) (Regulator of Fas-induced apoptosis Toso) FCMR FAIM3 TOSO
Human
IHC,ELISA
IHC 1:20-1:200ELISA 1:5000-1:20000
43.146 kDa ;
FCMR FAIM3 TOSO
o60667
Recombinant Human Fas apoptotic inhibitory molecule 3 protein (18-251AA)
Rabbit
Polyclonal
IgG
Cell biology
>95%, Antigen Affinity Purified
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20°C. Do not aliquot the antibody
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
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