Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)] FASLG APT1LG1 CD95L FASL TNFSF6

Human

IHC,IF,ICC,ELISA

IHC 1:20-1:200
IF 1:50-1:500
ICC 1:100-1:400
ELISA 1:5000-1:20000

31.485 kDa ;

FASLG APT1LG1 CD95L FASL TNFSF6

p48023

https://www.uniprot.org/uniprotkb/p48023

Recombinant Human Tumor necrosis factor ligand superfamily member 6 protein (103-281AA)

Rabbit

Polyclonal

IgG

Cell biology; Immunology; Stem cells

>95%, Protein G purified

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Store at -20°C. Do not aliquot the antibody