Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7521911, PubMed:8123008, PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:20477940). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).

Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3) SLC1A3 EAAT1 GLAST GLAST1

Human

IHC,IF,ICC,ELISA

IHC 1:200-1:500
IF 1:100-1:500
ICC 1:100-1:400
ELISA 1:5000-1:20000

59.572 kDa ;

SLC1A3 EAAT1 GLAST GLAST1

p43003

https://www.uniprot.org/uniprotkb/p43003

Recombinant Human Excitatory amino acid transporter 1 protein (146-236AA)

Rabbit

Polyclonal

IgG

Transmembrane

Others

>95%, Protein G purified

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Store at -20°C. Do not aliquot the antibody