May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins (By similarity). May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance (PubMed:15946952). May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating \\\\\\'Lys-48\\\\\\'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423).

RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Cyp60) (hCyP-60) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) (Rotamase PPIL2) PPIL2

Human

IHC,ELISA

IHC 1:20-1:200
ELISA 1:5000-1:20000

58.823 kDa ;

PPIL2

q13356

https://www.uniprot.org/uniprotkb/q13356

Recombinant Human Peptidyl-prolyl cis-trans isomerase-like 2 protein (1-260AA)

Rabbit

Polyclonal

IgG

Nucleus localization

Signal transduction

>95%, Antigen Affinity Purified

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20°C. Do not aliquot the antibody