Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Mitochondrial import inner membrane translocase subunit Tim8 A (Deafness dystonia protein 1) (X-linked deafness dystonia protein) TIMM8A DDP DDP1 TIM8A

Human

IHC,ELISA

IHC 1:20-1:200
ELISA 1:5000-1:20000

10.998 kDa ;

TIMM8A DDP DDP1 TIM8A

o60220

https://www.uniprot.org/uniprotkb/o60220

Recombinant Human Mitochondrial import inner membrane translocase subunit Tim8 A protein (1-97AA)

Rabbit

Polyclonal

IgG

Transmembrane

Neuroscience; Signal transduction

>95%, Antigen Affinity Purified

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20°C. Do not aliquot the antibody