Renin catalyzes the first step in the activation pathway of angiotensinogen-a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Mouse IgG1

3C10

Renin protein

Human RENIN

Purified : IgG / Liquid
Purfication : Affinity chromatography on Protein G
Buffer system : 10 mM Hepes , 75 mM NaCl , pH 7.5, containing 0.05% Procline 300

ELISA 1:10000-1:5000000

Stored at -20°C or below until use. Avoid repeated freezing and thawing cycles.

#D10000 PTH[3H19-B] Mouse mAb
#D10001 PTH[4G4] Mouse mAb
#T30000 Digoxin[1B9] Mouse mAb
#T30001 Digoxin[2N7] Mouse mAb
#T30003 Digoxin[2N7] mAb (HRP Coujugated)