Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.

Neurogenic locus notch homolog protein 2 [Precursor], Notch 2, hN2, Notch 2 extracellular truncation, Notch 2 intracellular domain, NOTCH2

Q04721

110 kDa

Rabbit IgG

Human,Mouse,Rat

WB 1:500-1:2000

	Western blot analysis of NOTCH2 (Cleaved-Ala1734) expression in Jurkat cells, treated with etoposide

Store at -20 °C. Stable for 12 months from date of receipt.