PU165319

货号 规格 价格(¥)
PU165319S 50μl
PU165319M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-CD31 antibody

Datasheet

Background

PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas, such as Kaposi's sarcoma and carcinomas. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial cells in histological tissue sections. This can help to evaluate the degree of tumour angiogenesis, which can imply a rapidly growing tumor

Alternative Name

Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31) PECAM1

Reactivity

Human,Mouse,Rat

Predicted Reactivity

Application

WB,IHC,IF,ICC,FC

Application Image

Recommended Dilution

WB 1:1000
IHC 1:1000-1:5000
IF 1:100-1:400
ICC 1:200
FC 1:100-1:200

Mol Weight

82 kDa (Observed: 130 kDa)

Gene Symbol

PECAM1

Uniprot

swissprot: p16284 human;swissprot: q08481 mouse

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Transmembrane

Research Area

Stem cells->Mesenchymal Stem Cells->Surface Molecules;Stem cells->Hematopoietic Progenitors->Lymphoid->T Lymphocytic Lineage;Cancer->Invasion/microenvironment->ECM->Cell adhesion->Other;Cancer->Invasion/microenvironment->Angiogenesis->ECM enzymes->Cathespins;Cancer->Tumor biomarkers->Tumor antigens;Cancer->Tumor immunology->CD markers

Positive control

THP-1,HUVEC,Hela,SW480,NIH/3T3,Jurkat,human kidney tissue

Conjugation

Modification

Purification

Peptide affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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