13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Ras superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp12 (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein. This antibody is predicted to react with H-Ras, N-Ras and K-Ras.
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras) NRAS HRAS1
Human,Mouse,Rat
WB,IHC,IF,ICC,FC
WB 1:1000IHC 1:200IF 1:100-1:400ICC 1:100FC 1:1000
21 kDa
NRAS HRAS1
swissprot: p01111;swissprot: p01112;swissprot: p01116
Rabbit
Polyclonal
Rabbit IgG
Transmembrane
Cell Biology->Cell Cycle->Cell Cycle Inhibitors->Other;Cell Biology->Cell Cycle->Cell Cycle Inhibitors->Cip / Kip;Cell Biology->Cell Cycle->Kinases/Phosphatases->Other;Cell Biology->Apoptosis->Intracellular->Associated Proteins;Cancer->Signal transduction->G protein signaling->Small G proteins->Ras family;Cancer->Cell cycle->Cell cycle inhibitors->Other;Cancer->Cell cycle->Cell cycle inhibitors->Cip/kip;Cancer->Cell cycle->Kinases/phosphatases->Other
PC12, MCF-7, 293T, Hela, HepG2, mouse brain tissue, mouse intestines tissue, rat brain tissue, human kidney tissue, mouse kidney tissue, mouse small intestine tissue, mouse pancreas tissue, rat kidney tissue, rat small intestine tissue, human liver cancer tissue.
Peptide affinity purified.
Liquid
1 mg/mL.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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