Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol. In the cytosol, other transporters sequester the dopamine into vesicles for storage and later release. Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses, although there may be an exception in the prefrontal cortex, where evidence points to a possibly larger role of the norepinephrine transporter.DAT is implicated in a number of dopamine-related disorders, including attention deficit hyperactivity disorder, bipolar disorder, clinical depression, alcoholism, and substance use disorder. The gene that encodes the DAT protein is located on human chromosome 5, consists of 15 coding exons, and is roughly 64 kbp long. Evidence for the associations between DAT and dopamine related disorders has come from a type of genetic polymorphism, known as a VNTR, in the DAT gene (DAT1), which influences the amount of protein expressed.
Sodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3) SLC6A3 DAT1
Human,Mouse,Rat
WB,IHC,IF,ICC,FC
WB 1:500-1:1000IHC 1:100-1:500IF 1:100-1:400ICC 1:50-1:200FC 1:50-1:100
Predicted band size: 68 kDa.
SLC6A3 DAT1
swissprot: q01959 human;swissprot: q61327 mouse;swissprot: p23977 rat
Rabbit
Polyclonal
Rabbit IgG
Transmembrane
Neuroscience->Neurotransmitter->Biogenic Amines->Dopamine;Neuroscience->Neurotransmitter->Transporters->Dopamine
Mouse brian tissue lysates, rat brain tissue, mouse brain tissue, SKOV-3, F9.
Peptide affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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订购专线:4006-123-828
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