Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
CD133 antigen, also known as prominin-1, is a glycoprotein that in humans is encoded by the PROM1 gene. It is a member of pentaspan transmembrane glycoproteins, which specifically localize to cellular protrusions. When embedded in the cell membrane, the membrane topology of prominin-1 is such that the N-terminus extends into the extracellular space and the C-terminus resides in the intracellular compartment. The protein consists of five transmembrane segments, with the first and second segments and the third and fourth segments connected by intracellular loops while the second and third as well as fourth and fifth transmembrane segments are connected by extracellular loops. While the precise function of CD133 remains unknown, it has been proposed that it acts as an organizer of cell membrane topology. CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastoma, neuronal and glial stem cells, various pediatric brain tumors, as well as adult kidney, mammary glands, trachea, salivary glands, uterus, placenta, digestive tract, testes, and some other cell types.
Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133) PROM1 PROML1 MSTP061
Human
WB,FC
WB 1:500-1:2000FC 1:50-1:100
Predicted band size 100 kDa.
PROM1 PROML1 MSTP061
swissprot: o43490 human
Rabbit
Polyclonal
Rabbit IgG
Transmembrane
Neuroscience->Cell Type Marker->Neural Stem Cell marker;Stem cells->Neural Stem Cells->Surface Molecules;Stem cells->Signaling Pathways->TGF beta->Cytoplasmic
SW620, HT-29 cell lysates, SW480 cell lysates, human kidney tissue, F9.
Peptide affinity purified.
Liquid
1 mg/ml
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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