Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
catalytic activity:L-cysteine + O(2) = 3-sulfinoalanine. cofactor:Binds 1 iron ion per subunit. Zinc to a much lesser extent. cofactor:IRON; NAD(P)H. Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. induction:In hepatoblastoma HepG2 cells, down-regulated by phorbol 12-myristate 13-acetate. pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2. PTM:The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen. Belongs to the cysteine dioxygenase family. subunit:Monomer. tissue specificity:Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma HepG2 cells.
Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I) CDO1
Human,Mouse,Rat
WB
WB 1:500-1:2000
22 kDa
CDO1
swissprot: q16878 human
Rabbit
Polyclonal
Rabbit IgG
Inflammatory response #Lactation
Brain,Epithelium,Liver,
Immunogen affinity purified.
Liquid
1 mg/mL.
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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