13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The human PPP1R9A gene encoding neurabin I is adjacent to SGCE, PEG10, and ASB4. Neurabin I (neural tissue specific F-actin-binding protein I) was originally purified from rat brain and has been characterised as a key candidate molecule in synaptic formation and function. It has also been shown that neurabin I is highly concentrated in the synapse of developed neurons and is involved in neurite formation. The deduced 1098 amino acid sequence for rat neurabin I contains an F-actin-binding domain, a PDZ domain, and coiled-coil domains. As the name indicates, the expression of the gene and protein was shown to be brain specific in adult rat tissues. The gene symbol is based on ‘‘protein phosphatase 1, regulatory (inhibitor) subunit 9A'' because neurabin I has been shown to bind protein phosphatase I (PP1) and inhibit its activity. The PP1/ neurabin I complex has been demonstrated to regulate actin cytoskeleton dynamics. Furthermore, molecules implicated in the control of neuronal morphology, such as p70S6K and kalirin-7 (a GTP-exchange factor), have been identified to bind the PDZ domain of neurabin I. Lastly, the C-terminus of neurabin I binds the trans-Golgi protein TGN38, suggesting it is a multi-functional molecule that regulates membrane and cytoskeletal functions.
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A) PPP1R9A KIAA1222
Human,Mouse,Rat
WB,IHC,IF,ICC,FC
WB 1:500-1:1000IHC 1:100-1:500IF 1:100-1:400ICC 1:50-1:100FC 1:50-1:100
Predicted band sizes: 123/140/145/154 kDa
PPP1R9A KIAA1222
swissprot: q9ulj8 human;swissprot: o35867 rat;swissprot: q7tn74 mouse
Rabbit
Polyclonal
Rabbit IgG
Rat brain tissue, SH-SY5Y, human liver carcinoma tissue, mouse brain tissue.
Protein affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
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