Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The C-X-C or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemo-attractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB and CXCR-4 (also known as LESTR or fusin). CXCR-4 is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. CXCR-4 has been identified as the major co-receptor for T-tropic HIV-1 and SDF-1 has been shown to inhibit HIV-1 infection.
C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184) CXCR4
Human,Rat
WB,IF,ICC,FC
WB 1:500-1:1000IF 1:100-1:400ICC 1:500-1:2000FC 1:50-1:100
45 kDa
CXCR4
swissprot: p61073 human;swissprot: o08565 rat
Rabbit
Polyclonal
Rabbit IgG
Transmembrane
Immunology->Adaptive Immunity->Regulatory T Cells;Immunology->Immune System Diseases->Antiviral Signaling->HIV-related;Immunology->Innate Immunity->Chemokines->Alpha Chemokine Rec. (CXCR);Stem cells->Hematopoietic Progenitors->Surface Molecules;Stem cells->Neural Stem Cells->Surface Molecules;Stem cells->Signaling Pathways->TGF beta->Cytoplasmic;Microbiology->Interspecies Interaction->Host Virus Interaction;Cancer->Cancer Metabolism->Response to hypoxia;Metabolism->Pathways and Processes->Metabolism processes->Hypoxia
293, K562, Hela, HUVEC, rat lung tissue, human tonsil tissue, human liver tissue, THP-1.
Peptide affinity purified.
Liquid
1 mg/mL.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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订购专线:4006-123-828
销售电话:13916964679(微信同号)
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华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
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