PU477984

货号 规格 价格(¥)
PU477984S 50μl
PU477984M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-SLFN12 antibody

Datasheet

Background

Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. All members of the Schlafen family contain a conserved core domain and are substantially diversified at the N terminus. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection and its induction leads to G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. Slfn1 and Slfn2 are both unregulated during the double-positive (DP) and single-positive (SP) stages of thymocyte development, whereas Slfn4 is down regulated at these stages. Changes in Schalfen protein expression may contribute to phenotypic differences seen in thymic subsets. Slfn12 (schlafen family member 12), also known as SLFN3, is a 578 amino acid protein belonging to the Schlafen family.

Alternative Name

Ribonuclease SLFN12 (EC 3.1.-.-) (Schlafen family member 12) SLFN12

Reactivity

Human

Predicted Reactivity

Application

WB,IHC,FC

Application Image

Recommended Dilution

WB 1:500-1:1000
IHC 1:50-1:200
FC 1:50-1:100

Mol Weight

67 kDa

Gene Symbol

SLFN12

Uniprot

swissprot: q8iym2 human

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Research Area

Positive control

U937 cell lysate, HL-60 cell lysate, human lung tissue, human prostate tissue, human small intestine tissue, human pancreas tissue, 293.

Conjugation

Modification

Purification

Peptide affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

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订购专线:4006-123-828

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技术支持:15618194176(微信同号)

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徐经理:手机15618191473(微信同号)
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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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