Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Calcium-activated substrate recognition component of a SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Unlike many F-box proteins, FBXL2 doesn't seem to target phosphodegron within its substrates but rather calmodulin-binding motifs. Targets PCYT1A for its monoubiquitination and degradation, this is antagonized by calmodulin (By similarity). Targets the cyclins CCND2 and CCND3 for polyubiquitination and degradation, leading to cell-cycle arrest in G(0), also antagonized by calmodulin. Binds to hepatitis C virus non-structural protein 5A (NS5A) in a reaction crucial for hepatitis C virus RNA replication.
F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3) FBXL2 FBL2 FBL3
Human,Mouse,Rat
WB,IHC,IF,ICC,FC
WB 1:1000-1:10000IHC 1:2000IF 1:100-1:400ICC 1:50-1:200FC 1:1000
49 kDa
FBXL2 FBL2 FBL3
swissprot: q9ukc9 human
Rabbit
Polyclonal
Rabbit IgG
Transmembrane
proteolysis,
Mouse liver tissue lysate, mouse heart tissue lysate, SiHa, rat liver tissue lysate, A431, HUVEC, SH-SY5Y, human liver tissue, human kidney tissue, human pancreas tissue, mouse brain tissue.
Protein A affinity purified.
Liquid
1 mg/mL.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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华南经销商负责(广东,广西,福建,海南):
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