PU949015

货号 规格 价格(¥)
PU949015S 50μl
PU949015M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-NF-κB p65 antibody

Datasheet

Background

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression.

Alternative Name

Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3) RELA NFKB3

Reactivity

Human,Mouse,Rat,Zebrafish

Predicted Reactivity

Application

WB,IHC,FC

Application Image

Recommended Dilution

WB 1:1000-1:2000
IHC 1:200
FC 1:50-1:100

Mol Weight

65 kDa

Gene Symbol

RELA NFKB3

Uniprot

swissprot: q04206 human;swissprot: q04207 mouse

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Polyclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Research Area

Neuroscience->Neurology process->Neurodegenerative disease->Alzheimer's disease->Other;Microbiology->Interspecies Interaction->Host Virus Interaction;Microbiology->Interspecies Interaction->Host Immune Response;Microbiology->Interspecies Interaction->Disease;Cell Biology->Apoptosis->Intracellular->NFkB->RelA;Cancer->Signal transduction->Nuclear signaling->NFkB pathway;Cancer->Signal transduction->Other;Cancer->Cell Death->Apoptosis->Apoptosis Markers->NFkB->RelA (p65);Metabolism->Types of disease->Obesity

Positive control

Hela, A549, PC12, mouse embryonic stem cell NIH/3T3, human breast carcinoma tissue, human lung carcinoma tissue

Conjugation

Modification

Purification

Peptide affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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技术支持:15618194176(微信同号)

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南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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