TU243403

货号 规格 价格(¥)
TU243403S 50μl
TU243403M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-BMP15 antibody

Datasheet

Background

Bone morphogenetic protein 15 is a protein that in humans is encoded by the BMP15 gene. It's mainly involved in folliculogenesis. The protein encoded by this gene is a member of the TGF-β superfamily. It is a paracrine signaling molecule involved in oocyte and follicular development. Using Northern blot analysis, BMP15 has been shown to be exclusively expressed in the ovaries. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Promotion of growth and maturation of ovarian follicles, starting from the primary gonadotrophin-independent phases of folliculogenesis. Regulation of the sensitivity of granulosa cells to follicle-stimulating hormone (FSH) action, contributing to the determination of the number of eggs that are ovulated. Prevention of granulosa cell apoptosis. Promotion of developmental competence of oocytes. Defects in BMP15 are associated with primary ovarian insufficiency. BMP15may represent a biomarker of ovarian response to ovarian stimulation or oocyte quality.

Alternative Name

Bone morphogenetic protein 15 (BMP-15) (Growth/differentiation factor 9B) (GDF-9B) BMP15 GDF9B

Reactivity

Human,Mouse,Rat

Predicted Reactivity

Application

WB,IHC

Application Image

Recommended Dilution

WB 1:500-1:2000
IHC 1:200-1:1000

Mol Weight

45 kDa (Predicted band size)

Gene Symbol

BMP15 GDF9B

Uniprot

swissprot: o95972 human;swissprot: q9z0l4 mouse

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Monoclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Research Area

Stem cells->Signaling Pathways->TGF beta->Secreted

Positive control

Hela, mouse ovary tissue.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

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技术支持:15618194176(微信同号)

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北方及西南经销商负责:

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

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