13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Mammalian ferritins consist of 24 subunits made up of two types of polypeptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. The gene encoding human ferritin heavy chain maps to chromosome 11q13 and the human ferritin light chain gene maps to chromosome 19q13.3-q13.4.
Ferritin light chain (Ferritin L subunit) FTL
Human,Mouse,Zebrafish,Rat
WB,IHC,IF,ICC,FC
WB 1:5000-1:20000IHC 1:1000IF 1:200ICC 1:100FC 1:1000
21 kDa
FTL
swissprot: p02792 human;swissprot: p02794 human;swissprot: p09528 mouse;swissprot: p29391 mouse;swissprot: p02793 rat;swissprot: p19132 rat
Rabbit
Monoclonal
Rabbit IgG
Neuroscience->Neurology process->Neurogenesis;Neuroscience->Neurology process->Neurodegenerative disease->Alzheimer's disease->Other;Metabolism->Pathways and Processes->Mitochondrial Metabolism->Mitochondrial markers;Metabolism->Pathways and Processes->Cofactors, Vitamins / minerals->Vitamins / minerals;Metabolism->Types of disease->Neurodegenerative disease
Zebrafish tissue lysates, hybrid fish (crucian-carp) liver tissue lysates, mouse ovary tissue lysate, mouse liver tissue lysate, human liver tissue lysate, SHG-44, MCF-7, SH-SY5Y, human spleen tissue.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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