13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex com-prising a catalytic α subunit and regulatory β and γ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming bio-synthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The Human,Mouse,Rat AMPKα1 and AMPKα2 genes encode 548 amino acid and 552 amino acid proteins, respectively. Human,Mouse,Rat AMPKβ1 encodes a 271 amino acid protein and Human,Mouse,Rat AMPKβ2 encodes a 272 amino acid protein. The Human,Mouse,Rat AMPKγ1 gene encodes a 331 amino acid protein. Human,Mouse,Rat AMPKγ2 and AMPKγ3, which are 569 and 492 amino acid proteins, respectively, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex.
5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb) PRKAB1 AMPK
Human,Mouse,Rat
WB,IHC,IF,ICC,FC
WB 1:500-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100FC 1:50-1:100
38 kDa
PRKAB1 AMPK
swissprot: q9y478 human,mouse,rat;swissprot: q9r078 mouse;swissprot: p80386 rat
Rabbit
Monoclonal
Rabbit IgG
Cancer->Cancer Metabolism->Metabolic signaling pathway->Integration of energy metabolism;Metabolism->Pathways and Processes->Metabolic signaling pathways->Energy transfer pathways->Integration of energy;Metabolism->Pathways and Processes->Metabolic signaling pathways->Lipid and lipoprotein metabolism->Fatty acids;Metabolism->Types of disease->Cancer
A431 cell lysates, Human,Mouse,Rat smooth muscle tissue, A431.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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