13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode guanine nucleotide-binding proteins that are ubiquitously expressed in vertebrate cells. c-H- and c-K-Ras are cellular homologs of the v-H and v-K-Ras sequences originally isolated from the Harvey and Kirsten strains of rat sarcoma virus. Ras-encoded proteins bind GDP and GTP with high affinity and possess a low level intrinsic GTPase activity that can be stimulated over 100-fold by interaction with cytosolic GTPase activating protein (GAP), a potential effector for Ras p21 function. Point mutations at amino acids 12, 13, 59 and 61 within domains responsible for GTP binding and hydrolysis activate Ras proteins to their oncogenic form and block the ability of the GTPase activity to be stimulated by GAP. Several additional proteins with GAP activity have been identified and shown to interact with p21 Ras or other members of the Ras gene family.
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras) NRAS HRAS1
Human,Mouse,Rat,Zebrafish
WB,IF,ICC,IP,FC
WB 1:1000-1:2000IF 1:100-1:400ICC 1:100-1:500IP 1:50FC 1:100
21 kDa
NRAS HRAS1
swissprot: p01111 human;swissprot: p01112 human;swissprot: p01116 human;swissprot: p08556 mouse;swissprot: p32883 mouse;swissprot: q61411 mouse;swissprot: p08644 rat;swissprot: p20171 rat;swissprot: q04970 rat
Rabbit
Monoclonal
Rabbit IgG
Transmembrane
Cell Biology->Cell Cycle->Cell Cycle Inhibitors->Other;Cell Biology->Cell Cycle->Cell Cycle Inhibitors->Cip / Kip;Cell Biology->Cell Cycle->Kinases/Phosphatases->Other;Cell Biology->Apoptosis->Intracellular->Associated Proteins;Cancer->Signal transduction->G protein signaling->Small G proteins->Ras family;Cancer->Cell cycle->Cell cycle inhibitors->Other;Cancer->Cell cycle->Cell cycle inhibitors->Cip/kip;Cancer->Cell cycle->Kinases/phosphatases->Other
293T cell lysate, MCF-7 cell lysate, Hela cell lysate, zebrafish tissue lysate, Hela, MCF-7, PC-12.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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