Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Neuronal cell fate decisions are directed in Drosophila by NUMB, a signaling adapter protein with two protein-protein interaction domains: a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR). Mammalian NUMB homologs play a role in the determination of cell fates during development and bind with EPS15, LNX1, and NOTCH1. Conditional mouse mutants with deletion of NUMB in developing sensory ganglia show a reduction in axonal arborization in afferent fibers. Changes in cellular calcium homeostasis influences NUMB-dependent cell fate decisions during development of the nervous system. Chicken NUMB (c-NUMB) protein is localized to the basal cortex of mitotic neuroepithelial cells.
Protein numb homolog (h-Numb) (Protein S171) NUMB C14orf41
Human,Mouse,Rat
WB,IHC,IF,ICC
WB 1:1000-1:5000IHC 1:50-1:100IF 1:100-1:400ICC 1:50-1:200
71 kDa
NUMB C14orf41
swissprot: p49757 human;swissprot: q9qzs3 mouse;swissprot: q2lc84 rat
Rabbit
Monoclonal
Rabbit IgG
Transmembrane
Neuroscience->Neurology process->Notch Pathway
A431 cell lysates, Hela, A431, NIH/3T3, mouse brain tissue, rat adrenal gland tissue, mouse kidney tissue.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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