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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The baculovirus protein p35 inhibits virally-induced apoptosis of invertebrate and mammalian cells and may function to impair the clearing of virally infected cells by the immune system of the host. This is accomplished at least in part by the ability of p35 to block both TNF- and FAS-mediated apoptosis through the inhibition of the ICE family of serine proteases. Two mammalian homologs of baculovirus p35, referred to as inhibitor of apoptosis protein (IAP) 1 and 2, share an amino-terminal baculovirus IAP repeat (BIR) motif and a carboxy-terminal RING finger. Although the c-IAPs do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. Additional IAP family members include ILP (for IAP-like protein) and survivin. ILP inhibits activated caspase-3, leading to the resistance of FAS-mediated apoptosis. Survivin (also designated TIAP) is expressed during the G2/M phase of the cell cycle and associates with microtubules of the mitotic spindle. Increased caspase-3 activity is detected when a disruption of survivin-microtubule interactions occurs.
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin) BIRC5 API4 IAP4
Human,Mouse,Rat
WB,IHC,IF,ICC,FC
WB 1:1000IHC 1:200-1:500IF 1:50-1:200ICC 1:100FC 1:1000
16 kDa
BIRC5 API4 IAP4
swissprot: o15392 human;swissprot: o70201 mouse
Rabbit
Monoclonal
Rabbit IgG
Neuroscience->Cell Type Marker->Glia marker->Astrocyte marker;Cell Biology->Apoptosis->Intracellular->Survivin / IAPs;Cancer->Invasion/microenvironment->Apoptosis->Caspases;Cancer->Invasion/microenvironment->Apoptosis->Cytochrome C;Cancer->Invasion/microenvironment->Apoptosis->Detection kits->Annexin V;Cancer->Invasion/microenvironment->Angiogenesis->Angiogenic growth factors;Cancer->Invasion/microenvironment->Angiogenesis->ECM enzymes->TIMPs;Cancer->Invasion/microenvironment->Angiogenesis->Angiogenic inhibitory factors;Cancer->Invasion/microenvironment->Angiogenesis->Other;Cancer->Invasion/microenvironment->Hypoxia->HIF;Cancer->Invasion/microenvironment->Hypoxia->Hypoxia-related proteins;Cancer->Tumor biomarkers->Tumor antigens;Cancer->Tumor biomarkers->Enzymes->Other;Cancer->Cell Death->Apoptosis->Receptors->Death receptors ligands->IAPs
Hela, human tonsil tissue, mouse testis tissue, human lymph node tissue.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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