13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. It interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD. MAFbx is specifically expressed in cardiac and skeletal muscle.
F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx) FBXO32
Human,Mouse,Rat
WB,IF,ICC
WB 1:2000IF 1:100-1:400ICC 1:50-1:200
41 kDa
FBXO32
swissprot: q969p5 human;swissprot: q9cpu7 mouse;swissprot: q91z62 rat
Rabbit
Monoclonal
Rabbit IgG
Stem cells->Mesenchymal Stem Cells->Myogenesis;Cell Biology->Proteolysis / Ubiquitin->Proteasome / Ubiquitin->Ubiquitin E3 Enzymes->SCF Complex E3 Ligase;Cell Biology->Proteolysis / Ubiquitin->Proteasome / Ubiquitin->Ubiquitin E3 Enzymes->F Box E3 Ligase
Mouse skeletal muscle tissue lysates, A431, L6.
Protein A affinity purified.
Liquid
1 mg/mL.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
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华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
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