TU424666

货号 规格 价格(¥)
TU424666S 50μl
TU424666M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

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   植物BPP法变性蛋白提取

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经典一抗-alpha+beta Synuclein antibody

Datasheet

Background

The synucleins, including α-synuclein (also designated NACP for nonamyloid component precursor), β-synuclein (also designated PNP 14 for phospho-neuroprotein 14) and γ-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. Synucleins are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-Synuclein, identified as a component of Alzheimer's disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of α-synuclein and β-synuclein may be important during hematopoetic cell differentiation. A mutant form of α-synuclein is found in patients with early onset Parkinson's disease. γ-Synuclein is associated with axonal pathology in Parkinson's disease.

Alternative Name

Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP) SNCA NACP PARK1

Reactivity

Human,Mouse,Rat

Predicted Reactivity

Application

WB,IHC,IF,ICC,FC

Application Image

Recommended Dilution

WB 1:1000-1:2000
IHC 1:5000
IF 1:50-1:200
ICC 1:50-1:200
FC 1:50-1:100

Mol Weight

14 kDa

Gene Symbol

SNCA NACP PARK1

Uniprot

swissprot: p37840 human;swissprot: q16143 human;swissprot: o55042 mouse;swissprot: q91zz3 mouse;swissprot: p37377 rat;swissprot: q63754 rat

Uniprot link

Immunogen

Immunogen Range

Source

Rabbit

Clonality

Monoclonal

Isotype

Rabbit IgG

Specificity

Subcellular location

Research Area

Neuroscience->Sensory System->Visual system;Neuroscience->Neurology process->Neurodegenerative disease->Alzheimer's disease->Other;Neuroscience->Neurology process->Neurodegenerative disease->Alzheimer's disease->Tangles Tau;Neuroscience->Neurology process->Neurodegenerative disease->Parkinson's disease->Synuclein

Positive control

Rat brain tissue lysates, mouse brain tissue lysates, Hela, N2A, SH-SY5Y, rat brain tissue, mouse brain tissue.

Conjugation

Modification

Purification

Protein A affinity purified.

Formulation

Liquid

Concentration

1 mg/mL.

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

产品介绍

Clone

Target

波长

Storage

Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.

注意事项

Companion Products

Important

Comments

RRID

客户评价

艾比玛特医药科技(上海)有限公司
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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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