Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene apos;mothers against decapentaplegicapos; (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3) SMAD3 MADH3
Human,Mouse,Rat
WB,IHC
WB 1:500-1:2000IHC 1:50-200
60 kDa
SMAD3 MADH3
swissprot: p84022 human;swissprot: q15796 human
Rabbit
Polyclonal
Rabbit IgG
Cancer->Cancer Metabolism->Response to hypoxia;Cancer->Signal transduction->Nuclear signaling->SMAD family;Cancer->Signal transduction->Other;Cancer->Growth factors->TGF;Metabolism->Pathways and Processes->Metabolism processes->Hypoxia
Chronic myeloid leukemia cell,Colon adenocarcinoma,Epithelium,Kidney,Pancreas,Place
Immunogen affinity purified.
Liquid
1 mg/mL.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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订购专线:4006-123-828
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华南经销商负责(广东,广西,福建,海南):
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