SDR O Antibody_经典一抗 -

产品类型

蛋白质研究服务
目录抗体
经典一抗
二抗
标签/内参抗体
Beads抗体
病理诊断与药物研发
直标流式抗体
模式小物种抗体
辅助产品
小分子抑制剂
核酸研究试剂
细胞因子
重组蛋白
酶标试剂盒

MG641723

货号规格价格(￥)

MG641723S 50μl

MG641723M 100μl

以上产品均有现货供应

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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。

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经典一抗-SDR O Antibody

Datasheet

Description

Plays a crucial role in the formation of the epidermal permeability barrier (PubMed:31671075). Catalyzes the NAD+-dependent dehydrogenation of the linoleate 9,10-trans-epoxy-11E-13-alcohol esterified in omega-O-acylceramides (such as in N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]-acylsphing-4E-enine) to the corresponding 13-ketone, the reactive moiety required for binding of epidermal ceramides to proteins (PubMed:31671075). Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity (PubMed:19703561).

Alternative Names

Short-chain dehydrogenase/reductase family 9C member 7 (SDR9C7) (EC 1.1.1.-) (O-acylceramide dehydrogenase) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S)
SDR9C7 RDHS SDRO RDHS; SDR-O; SDRO

UniProt

Q8NEX9

Reactivity

Human, Rat

Application

WB,IHC,FC

Application Image

Recommended Dilution

WB 1:500
IHC 1:150
FC 1:100

Mol Weight

35.1 kDa

Source

Mouse

Immunogen

Full length human recombinant protein of human SDR9C7 (NP_683695) produced in E.coli.

Clonality

Monoclonal

Purification

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage

Store at -20 °C. Stable for 12 months from date of receipt.

HEK293T cells were transfected with the pCMV6-ENTRY control(Left lane) or pCMV6-ENTRY SDR9C7(Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates(5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SDR9C7(Cat# MG641723). Positive lysates can be purchased separately from Abmart.

	Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-SDR9C7 mouse monoclonal antibody.(Heat-induced epitope retrieval by 10mM citric buffer,pH6.0,100℃ for 10min,MG641723)
	Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-SDR9C7 mouse monoclonal antibody.(Heat-induced epitope retrieval by 10mM citric buffer,pH6.0,100℃ for 10min,MG641723)
	Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SDR9C7 mouse monoclonal antibody.(Heat-induced epitope retrieval by 10mM citric buffer,pH6.0,100℃ for 10min,MG641723)
	Immunohistochemical staining of paraffin-embedded Human bladder tissue within the normal limits using anti-SDR9C7 mouse monoclonal antibody.(Heat-induced epitope retrieval by 10mM citric buffer,pH6.0,100℃ for 10min,MG641723)

HEK293T cells transfected with either overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SDR9C7 antibody(MG641723),and then analyzed by flow cytometry.