13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3 . H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation . Plays a central role in the transcriptional activation of genes such as collagenase or insulin . Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription . Has also methyltransferase activity toward non-histone proteins such as CGAS, p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins . Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II . Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation . Monomethylates 'Lys-491' of CGAS, promoting interaction between SGF29 and CGAS (By similarity). .
Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9) SETD7 KIAA1717 KMT7 SET7 SET9
Human, Mouse, Rat
WB,FC
WB 1:500-2000FC 1:100
40.5 kDa
SETD7 KIAA1717 KMT7 SET7 SET9
q8wts6
Full length human recombinant protein of human SETD7(NP_085151) produced in HEK293 cell.
Mouse
Monoclonal
Mouse IgG
Nucleus localization
DNA damage #chromatin organization
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Liquid
0.31 mg/ml
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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