Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene. Caspase-6 has known functions in apoptosis, early immune response and neurodegenration in Huntington's and Alzheimer's disease. Caspase-6 is a member of the cysteine-aspartic acid protease (caspase) family. Caspase-6 plays a role in the early immune response via de-repression. It reduces the expression of the immunosuppressant cytokine interleukin-10 and cleaves the macrophage suppressing IRAK-M. With respect to neurodegeneration, caspase-6 cleaves HTT in Huntington's and APP in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)] CASP6 MCH2
Human
Mouse,Rat,Monkey,Dog,Pig,Horse,Sheep,Bovine,Rabbit,Hamster
WB,IP
WB 1:1000-1:2000IP 1:50
18,33kDa
Caspase-6
p55212
Rabbit
Monoclonal
Rabbit IgG
Apoptosis #proteolysis,
PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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