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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
CHRDL2 (chordin-related protein 2), also known as BNF1 (breast tumor novel factor 1) or CHL2 (chordin-like 2), is a 429 amino acid protein that belongs to the chordin family of proteins. CHRDL2 contains three VWFC (von Willebrand Factor type C) domains and is predominantly expressed in uterus and moderately expressed in prostate, liver, ovary, heart and testis. Due to alternative splicing events, CHRDL2 exists as five isoforms, namely isoform I, isoform II, isoform VII, isoform VIII and isoform IX. Two of these isoforms are secreted, while the other three localize to the cytoplasm. Functioning as a BMP-binding inhibitor, CHRDL2 directly interacts with BMPs and blocks their binding to BMP receptors, thereby inhibiting BMP activity. In breast, lung and colon tumors, CHRDL2 expression is upregulated, suggesting a possible role in tumorigenesis.
Chordin-like protein 2 (Breast tumor novel factor 1) (BNF-1) (Chordin-related protein 2) CHRDL2 BNF1 CHL2 UNQ765/PRO1557
Human
WB,IHC
WB 1:200-1000IHC 1:10-100
48kDa
25884
q6wn34
A synthetic peptide of human CHRDL2
Rabbit
Polyclonal
IgG
Cytoplasm
Chondrogenesis #Differentiation #Osteogenesis
Affinity purification
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Store at -20℃. Avoid freeze / thaw cycles.
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