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Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Vacuolar sorting proteins (VPSs) are required for trafficking normal endocytic and biosynthetic proteins to the vacuole and also play an important role in the budding process of cells. The ESCRT-II (endosomal sorting complex required for transport II) complex, which is involved in endocytosis of ubiquinated membrane proteins, is formed by Eap45, EAP30, and VPS25. These vacuolar sorting proteins are also involved in a multiprotein complex with RNA ploymerase II elongation factor (ELL). Eap45 (ELL-associated protein of 45 kDa), also known as vacuolar protein-sorting-associated protein 36, is a 386 amino acid protein containing a GLUE (GRAM-like ubiquitin-binding in Eap45) domain that mediates the binding to ubiquitin and phophoinosides. Since Eap45 colocalizes with ubiquinated proteins on late endosomes, it is likely that Eap45 plays a role in the endosomal sorting of ubiquniated cargo. There are two isoforms of Eap45 that exist as a result of alternative splicing events.
Vacuolar protein-sorting-associated protein 36 (ELL-associated protein of 45 kDa) (ESCRT-II complex subunit VPS36) VPS36 C13orf9 EAP45 CGI-145
Human,Mouse,Rat
WB,IHC
WB 1:200-1000IHC 1:25-100
44kDa
51028
q86vn1
A synthetic peptide of human VPS36
Rabbit
Polyclonal
IgG
Cytoplasm
Affinity purification
Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Store at -20℃. Avoid freeze / thaw cycles.
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订购专线：4006-123-828
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