Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
Interferon-inducible protein AIM2 (Absent in melanoma 2) AIM2
Human
WB,IHC
WB 1:1000-3000IHC 1:100-300
39kDa
9447
o14862
A synthetic peptide of Human AIM2
270-320/343aa
Rabbit
Polyclonal
IgG
Cytoplasm Nucleus
Antiviral defense #DNA damage #Inflammatory response #Innate immunity
Octanoic acid-ammonium sulfate precipitation
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
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