Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
APAF Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. Induced by E2F and p53 in apoptotic neurons. Monomer. Oligomerizes upon binding of cytochrome c and dATP. Oligomeric Apaf-1 and pro-caspase-9 bind to each other via their respective NH2-terminal CARD domains and consecutively mature caspase-9 is released from the complex. Pro-caspase-3 is recruited into the Apaf-1-pro-caspase-9 complex via interaction with pro-caspase-9. Interacts with APIP. 6 isoforms of the human protein are produced by alternative splicing.
Apoptotic protease-activating factor 1 (APAF-1) APAF1 KIAA0413
Human,Mouse
Rat,Dog,Pig,Cat,Horse,Sheep,Bovine,Rabbit,Hamster,Guinea Pig,Chicken
WB,IHC,IF,ICC
WB 1:500-1:2000IHC 1:50-1:200IF 1:50-1:200ICC 1:50-1:200
135kDa
APAF1 KIAA0413
o14727
A synthesized peptide derived from human APAF1
Rabbit
Monoclonal
Rabbit IgG
APAF1 Antibody detects endogenous levels of total APAF1
Apoptosis #Differentiation #Neurogenesis
Affinity-chromatography
PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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订购专线:4006-123-828
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程经理:手机18616261485(微信同号)
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