13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
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Product Information
| Description | Collagen I rabbit polyclonal |
| Protein full name | Collagen alpha-1(I) chain |
| Synonyms | COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse COL1A1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 138 kDa |
| Observed MW. | 120 kDa |
| Uniprot ID | P11087,P02452,P02454 |
Applications
| applications | species | dilution | Positive tissue |
| WB | Human, Mouse,Rat | 1:1000 | KB cell,liver cancer,lung,kidney |
| IHC | Human, Mouse,Rat | 1:1000-1:2000 | Bone，pancreas |
| IF | Human, Mouse,Rat | 1:100-1:1000 | skin，bone |
Background
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Images
 | Western blot analysis of CollagenI (T61022M) at dilution of 1:1000. Lane1: MCF7 cell lysate Lane2: Mouse cartilage tissue lysate Lane3: Mouse lung tissue lysate Lane4: Mouse skin tissue lysate Lane5: Mouse uterus tissue lysate Lane6: Mouse fibrotic liver tissue lysate Lane7: Rat cartilage tissue lysate Lane8: Rat lung tissue lysate Lane9: Rat skin tissue lysate |
 | Immunohistochemistry analysis of paraffin-embedded mouse liver using CollagenI (T61022M) at dilution of 1:2000 |
 | Immunohistochemistry analysis of paraffin-embedded mouse blood vessel using CollagenI (T61022M) at dilution of 1:2000 |
 | Immunofluorescence analysis of paraffin-embedded mouse lung using CollagenI (T61022M) at dilution of 1:2000 |
 | Immunofluorescence analysis of paraffin-embedded rat lung using CollagenI (T61022M) at dilution of 1:2000 |
 | Immunofluorescence analysis of paraffin-embedded mouse kidney using CollagenI (T61022M) at dilution of 1:2000 |
 | Immunofluorescence analysis of paraffin-embedded rat kidney using CollagenI (T61022M) at dilution of 1:2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Collagen alpha-1(I) chain (Alpha-1 type I collagen) COL1A1
Human,Rat,Mouse
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
139kD
COL1A1
P11087,P02452,P02454
Rabbit
Polyclonal
Rabbit IgG
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
AB_2936784
艾比玛特医药科技（上海）有限公司
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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