Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
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Product Information
| Description | FOXP3 rabbit polyclonal |
| Protein full name | Forkhead box protein P3 |
| Synonyms | FOXP3, AIID, DIETER, IPEX, JM2, PIDX, XPID, forkhead box P3 |
| Immunogen | Recombinant protein corresponding to Mouse FOXP3 |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 47KDa |
| Observed MW. | 50KDa |
| Uniprot ID | Q99JB6,Q9BZS1 |
Applications
| applications | species | dilution | Positive tissue |
| WB | Human,Mouse,Rat | 1:500-1:1000 | PC3,inflammatory spleen,thymus gland |
Background
FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body s own tissues.
Images
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Western blot analysis of FOXP3 (T61093-1M) at dilution of 1:800. Lane 1:MCF7 cell lysate Lane 2:PC3 cell lysate Lane 3:Mouse inflammatory spleen tissue lysate Lane 4:Mouse thymus gland tissue lysate Lane 5:Mouse spleen tissue lysate Lane 6:Rat thymus gland tissue lysate Lane 7:Rat inflammatory spleen tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
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订购专线:4006-123-828
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华南经销商负责(广东,广西,福建,海南):
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