13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
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Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
Chymase (EC 3.4.21.39) (Alpha-chymase) (Mast cell chymase 1) (Mast cell protease 5) (mMCP-5) (Mast cell protease I) Cma1 Mcpt5
Rat,Mouse
IHC,IF,ICC
IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
28kD
Cma1 Mcpt5
P21844,P50339
Rabbit
Polyclonal
Rabbit IgG
Product Information
| Description | Chymaserabbit polyclonal |
| Protein full name | Chymase |
Synonyms | Alpha-chymase, Mast cell chymase 1, Mast cell chymase 5, mMCP-5, Mast cell protease I, Cma1, Mcpt5 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to MouseChymase |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Secreted |
| Uniprot ID |
Applications
| Applications | IHC | IF |
| Species | Mouse,Rat | Mouse,Rat |
| Dilution | 1:1000-1:2000 | 1:500-1:1000 |
| Positive tissue | skin, stomach, uterus | skin, stomach, uterus |
Background
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
Images
| Immunohistochemistry analysis of paraffin-embedded mouseskinusing Chymase (T611085M) at dilution of 1:1000 |
| Immunohistochemistry analysis of paraffin-embeddedrat skinusing Chymase (T611085M) at dilution of 1:1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse stomachusing Chymase (T611085M) at dilution of 1:1000 |
| Immunohistochemistry analysis of paraffin-embedded rat stomachusing Chymase (T611085M) at dilution of 1:1000 |
| Immunohistochemistry analysis of paraffin-embedded rat uterususing Chymase (T611085M) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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