13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
ERC protein 2 (CAZ-associated structural protein 1) (CAST1) Erc2 Cast1 D14Ertd171e Kiaa0378
Human,Mouse
WB
WB 1:1000-1:2000
111kD
Erc2 Cast1 D14Ertd171e Kiaa0378
Q6PH08,Q8K3M6
Rabbit
Polyclonal
Rabbit IgG
Product Information
| Description | ATG3rabbit polyclonal |
| Protein full name | Ubiquitin-like-conjugating enzyme ATG3 |
Synonyms | Autophagy-related protein 3, Protein PC3-96, APG3-like, hApg3, ATG3, APG3,APG3L |
| Immunogen | Recombinantproteincorrespondingto HumanATG3 |
| Isotype | IgG |
| Purity | Affinity purification |
Predicted MW. | 36 kDa |
Observed MW. | 40kDa |
| Uniprot ID |
Applications
| Applications | WB |
| Species | Human,Mouse |
| Dilution | 1:500-1:1000 |
| Positive tissue | THP-2, A20, Hela, Jurkat |
Background
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.
Images
| Western blot analysis of ATG3 (T611131M) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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