13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity. .
Forkhead box protein O4 (Fork head domain transcription factor AFX1) FOXO4 AFX AFX1 MLLT7
Human,Rat
WB
WB 1:1000-1:2000
54kD
FOXO4 AFX AFX1 MLLT7
P98177,D4A433
Rabbit
Polyclonal
Rabbit IgG
Myogenesis #regulation of DNA-templated transcription,
Product Information
| Description | FOXO4rabbit polyclonal |
| Protein full name | Forkhead box protein O4 |
Synonyms | Fork head domain transcription factor AFX1, FOXO4, AFX,AFX1,MLLT7 |
| Immunogen | Recombinantproteincorrespondingto HumanFOXO4 |
| Isotype | IgG |
| Purity | Affinity purification |
Predicted MW. | 54 kDa |
Observed MW. | 54 kDa |
| Uniprot ID |
Applications
| Applications | WB |
| Species | Human,Rat |
| Dilution | 1:500-1:1000 |
| Positive tissue | 293T, MDA-MB-231, Jurkat |
Background
FOXO4, also named as AFX, AFX1 and MLLT7, is a transcription factor which involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1.FOXO down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Images
| Western blot analysis of FOXO4 (T611173M) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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