13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
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Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. .
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) MYH10
Human,Mouse
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
229kD
MYH10
P35580,Q61879,Q9JLT0
Rabbit
Polyclonal
Rabbit IgG
Cell adhesion #Cell shape
Product Information
| Description | MYH10rabbit polyclonal |
| Protein full name | Myosin-10 |
Synonyms | Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, Myh10, non-muscle IIb, NMMHC-B, NMMHC-IIB |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse MYH10 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Nuclear, Cytoplasm, Secreted |
Predicted MW. | 229 kDa |
Observed MW. | 229 kDa |
| Uniprot ID |
Applications
| Applications | WB | IHC | IF |
| Species | Human,Mouse | Mouse,Rat | Mouse,Rat |
| Dilution | 1:500-1:800 | 1:1000-1:2000 | 1:500-1:1000 |
| Positive tissue | brain, kidney | brain, kidney, ovary | brain, small intestine, colon, kidney |
Background
MYH10 (non-muscle II-b, NM IIB) is a member of non-muscle myosin II which plays fundamental roles in the maintenance of cell morphology, cell adhesion, and migration, as well as cell division. MYH10 is mainly present in nerve cells, megakaryocytes, and other non-muscle cells. It has been reported to mediate centrosome reorientation during cell migration and contribute to ciliogenesis. Overexpression of MYH10 has been observed in breast cancer.
Images
| Western blot analysis of MYH10 (T611186M) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded mousebrain using MYH10 (T611186M)at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat brainusing MYH10 (T611186M)at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using MYH10 (T611186M)at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat kidneyusing MYH10 (T611186M)at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat ovaryusing MYH10 (T611186M)at dilution of 1:2000 |
| Immunofluorescent analysis of paraffin-embeddedmouse brain using MYH10 (T611186M)at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embedded rat brainusing MYH10 (T611186M)at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embedded mouse small intestine using MYH10 (T611186M)at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embedded rat colonusing MYH10 (T611186M)at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embedded rat kidneyusing MYH10 (T611186M)at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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