13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes . Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). .
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa) EFTUD2 KIAA0031 SNRP116
Human,Rat,Mouse
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
110kD
EFTUD2 KIAA0031 SNRP116
Q15029,O08810
Rabbit
Polyclonal
Rabbit IgG
Product Information
| Description | EFTUD2rabbit polyclonal |
| Protein full name | 116 kDa U5 small nuclear ribonucleoprotein component |
Synonyms | Snrp116, Elongation factor Tu GTP-binding domain-containing protein 2, U5-116 kDa, Eftud2, U5 snRNP-specific protein,116 kDa |
| Immunogen | KLH conjugated Synthetic peptide corresponding to MouseEFTUD2 |
| Isotype | IgG |
| Purity | Affinity purification |
Subcellular location | Nucleus |
| Predicted MW. | 109 kDa |
| Observed MW. | 116 kDa |
| Uniprot ID |
Applications
| Applications | WB | IHC | IF |
| Species | Human,Mouse,Rat | Human,Mouse,Rat | Human,Mouse,Rat |
| Dilution | 1:500-1:1000 | 1:1000-1:2000 | 1:500-1:1000 |
| Positive tissue | brain, liver | lung cancer, prostate cancer, lung, brain, testis, kidney | prostate cancer, lung, placenta, liver, brain, testis, colon |
Background
EFTUD2 encodes the 116 kDa U5 small nuclear ribonecleoprotein (snRNP) component, also named SNU114, it has GTP binding activity and is required for pre-mRNA splicing. Evolutionarily conserved human snRNP protein (U5-116kDa) is homologous to the ribosomal elongation factor EF-2 (ribosomal translocase). Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM).
Images
| Western blot analysis of EFTUD2 (T611188M) at dilution of 1: 1000 Lane 1: U87 cell lysate Lane 2: NIH3T3 cell lysate Lane 3: PC12 cell lysate Lane 4: Mouse brain tissue lysate Lane 5: Mouse liver tissue lysate Lane 6: Rat brain tissue lysate |
| Immunohistochemistry analysis of paraffin-embedded human lung cancerusing EFTUD2 (T611188M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded human prostate cancerusing EFTUD2 (T611188M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse lung usingEFTUD2 (T611188M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat lungusing EFTUD2 (T611188M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using EFTUD2 (T611188M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat brainusing EFTUD2 (T611188M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat testisusing EFTUD2 (T611188M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat kidneyusing EFTUD2 (T611188M) at dilution of 1:2000 |
| Immunofluorescent analysis of paraffin-embeddedhuman prostate cancerusing EFTUD2 (T611188M) at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embeddedmouse lung using EFTUD2 (T611188M) at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embeddedmouse placenta using EFTUD2 (T611188M) at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embeddedmouse liver using EFTUD2 (T611188M) at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embedded rat brainusing EFTUD2 (T611188M) at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embedded rat testisusing EFTUD2 (T611188M) at dilution of 1:1000 |
| Immunofluorescent analysis of paraffin-embedded rat colonusing EFTUD2 (T611188M) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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