13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity). .
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5) KRT5
Human,Mouse
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
63kD
KRT5
P13647,Q922U2,Q6P6Q
Rabbit
Polyclonal
Rabbit IgG
Keratinization
Product Information
| Description | Cytokeratin 5 rabbit polyclonal |
| Protein full name | Keratin, type II cytoskeletal 5 |
Synonyms | Cytokeratin-5, CK-5, Keratin-5, K5, Type-II keratin Kb5, Krt5, Krt2-5 |
| Immunogen | Recombinantproteincorrespondingto Mouse Cytokeratin 5 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm, Cell Membrane |
Predicted MW. | 62 kDa |
Observed MW. | 62 kDa |
| Uniprot ID |
Applications
| Applications | WB | IHC | IF |
| Species | Human,Mouse | Human,Mouse,Rat | Human,Mouse,Rat |
| Dilution | 1:500-1:1000 | 1:1000-1:2000 | 1:1000-1:2000 |
| Positive tissue | skin | breast cancer, skin, bladder | ovary, breast, skin, esophagus, bladder |
Background
The protein encoded by this gene is a member of the keratin gene family. It is one type II keratin, is coexpressed with keratin 14 in stratified squamous epithelia. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex.
Images
| Western blot analysis of Cytokeratin 5 (T611246M) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human breast cancerusing CK5 (T611246M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded mouseskinusing CK5 (T611246M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat skinusing CK5 (T611246M) at dilution of 1:2000 |
| Immunohistochemistry analysis of paraffin-embedded rat bladderusing CK5 (T611246M) at dilution of 1:2000 |
| Immunofluorescent analysis of paraformaldehyde-fixedhuman ovaryusing CK5 (T611246M) at dilution of 1:2000 |
| Immunofluorescent analysis of paraformaldehyde-fixedhuman breastusing CK5 (T611246M) at dilution of 1:2000 |
| Immunofluorescent analysis of paraformaldehyde-fixedmouse skin using CK5 (T611246M) at dilution of 1:2000 |
| Immunofluorescent analysis of paraformaldehyde-fixedrat esophagus using CK5 (T611246M) at dilution of 1:2000 |
| Immunofluorescent analysis of paraformaldehyde-fixedrat bladderusing CK5 (T611246M) at dilution of 1:2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
艾比玛特医药科技（上海）有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
沪ICP备17056956号-2 艾比玛特医药科技（上海）有限公司
