13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. .
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5) KRT6A K6A KRT6D
Human,Mouse
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
61kD
KRT6A K6A KRT6D
P02538,P50446,Q4FZU2
Rabbit
Polyclonal
Rabbit IgG
Differentiation #Keratinization #Cytolysis #killing of cells of another organism
Product Information
| Description | Cytokeratin 6 rabbit polyclonal |
| Protein full name | Keratin, type II cytoskeletal 6A |
| Synonyms | Cytokeratin-6A, CK-6A, Keratin-6-alpha, mK6-alpha, Keratin-6A, K6A, Krt6a, Ker2,Krt2-6,Krt2-6a,Krt6 |
| Immunogen | Recombinantproteincorrespondingto Mouse Cytokeratin 6a |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm |
| Predicted MW. | 59 kDa |
| Observed MW. | 59 kDa |
| Uniprot ID | P02538, P50446, Q4FZU2 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human,Mouse | 1:500-1:1000 | skin |
| IHC | Human,Mouse,Rat | 1:1000-1:2000 | tonsils, skin, stomach |
| IF | Human, Mouse,Rat | 1:1000-1:2000 | skin, stomach |
Background
The protein encoded by this gene is a member of the keratin gene family. The Krt6 belongs to type II cytokeratins and consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita.
Images
| Western blot analysis of CK6 (T611247M) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human tonsilusing CK6 (T611247M) at dilution of 1:1000 |
| Immunohistochemistry analysis of paraffin-embedded mouseskinusing CK6 (T611247M) at dilution of 1:1000 |
| Immunohistochemistry analysis of paraffin-embedded rat skinusing CK6 (T611247M) at dilution of 1:1000 |
| Immunohistochemistry analysis of paraffin-embedded rat stomachusing CK6 (T611247M) at dilution of 1:1000 |
| Immunofluorescentanalysis ofparaformaldehyde-fixedmouse skin using CK6 (T611247M) at dilution of 1:1000 |
| Immunofluorescentanalysis ofparaformaldehyde-fixedrat stomachusing CK6 (T611247M) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 mu;g/mlBSA and 50% glycerol. |
NOTE:This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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