13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development . It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). .
Nuclear receptor subfamily 4 group A member 2 (Immediate-early response protein NOT) (Orphan nuclear receptor NURR1) (Transcriptionally-inducible nuclear receptor) NR4A2 NOT NURR1 TINUR
Human
WB,IHC,IF,ICC
WB 1:1000-1:2000IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
67kD
NR4A2 NOT NURR1 TINUR
P43354,Q06219,Q07917
Rabbit
Polyclonal
Rabbit IgG
Product Information
| Description | Nurr1 rabbit polyclonal |
| Protein full name | Nuclear receptor subfamily 4 group A member 2 |
Synonyms | NUR-related factor 1, Orphan nuclear receptor NURR1, Nr4a2, Nurr1 |
| Immunogen | Recombinantproteincorrespondingto Mouse Nurr1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm,Nucleus |
Predicted MW. | 67 kDa |
Observed MW. | 67 kDa |
| Uniprot ID |
Applications
| Applications | WB | IHC | IF |
| Species | Human, Mouse, Rat | Human,Mouse | Human,Mouse |
| Dilution | 1:500-1:800 | 1:200-1:800 | 1:200-1:800 |
| Positive tissue | brain | kidney cancer, breast cancer, tonsil, thyroid, brain, spleen | brain |
Background
NR4A2 belongs to the orphan nuclear receptor (NR) family referred to as NR4A family, which have been implicated in cell cycle regulation, apoptosis, inflammation, metabolism and more recently in carcinogenesis . NR4A2 also has a role in the expression of several proteins that are necessary for the synthesis and regulation of dopamine (DA), such as tyrosine hidroxilase, dopamine transporter, vesicular monoamine transporter 2, and cRET [PMID:22294735]. Act as a transcriptional regulator, NR4A2 is essential for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development.
Images
| Western blot analysis of Nurr1 (T611267M) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded human kidney cancerusing Nurr1 (T611267M) at dilution of 1:800 |
| Immunohistochemistry analysis of paraffin-embedded human breast cancerusing Nurr1 (T611267M) at dilution of 1:200 |
| Immunohistochemistry analysis of paraffin-embedded human tonsilusing Nurr1 (T611267M) at dilution of 1:400 |
| Immunohistochemistry analysis of paraffin-embedded human thyroidusing Nurr1 (T611267M) at dilution of 1:200 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using Nurr1 (T611267M) at dilution of 1:800 |
| Immunohistochemistry analysis of paraffin-embedded mouse spleenusing Nurr1 (T611267M) at dilution of 1:200 |
| Immunofluorescentanalysis ofparaformaldehyde-fixedmouse brain using Nurr1 (T611267M) at dilution of 1:400 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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