13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages . Inhibits the developmental program of IL17A effector gamma-delta T-cell subsets via regulating the transcription of T-cell lineage effector proteins . Required for the development of natural killer receptor-positive lymphoid tissue inducer T-cells . TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1 (By similarity). May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. .
Transcription factor 7 (TCF-7) (T-cell-specific transcription factor 1) (T-cell factor 1) Tcf7 Tcf-1 Tcf1
Human
WB
WB 1:1000-1:2000
46kD
Tcf7 Tcf-1 Tcf1
Q00417
Rabbit
Polyclonal
Rabbit IgG
regulation of DNA-templated transcription,
Product Information
| Description | PKC delta rabbit polyclonal |
| Protein full name | Protein kinase C delta type |
Synonyms | Tyrosine-protein kinase PRKCD, nPKC-delta, Protein kinase C delta type regulatory subunit, Protein kinase C delta type catalytic subunit, Sphingosine-dependent protein kinase-1, SDK1, Prkcd, Pkcd |
| Immunogen | Recombinantproteincorrespondingto Mouse PKC delta |
| Isotype | IgG |
| Purity | Affinity purification |
| Predicted MW. | 78 kDa |
| Observed MW. | 78-83 kDa |
| Uniprot ID | Q00417 |
Applications
| Applications | WB |
| Species | Human |
| Dilution | 1:500-1:1000 |
| Positive Tissue | tHela, MCF7, A431 |
Background
The protein encoded by this gene is a member of the PKC subfamily, AGC Ser/Thr protein kinase family of enzymes. It is a Ca++ independent and phospholipid dependent ubiquitous enzyme that participates in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types.
Images
| Western blot analysis of PKC delta (T611383M) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: MCF7 cell lysate Lane 3: A431 cell lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 mu;g/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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