13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
High mobility group AT-hook 2 Hmga2
Rat,Mouse
IHC,IF,ICC
IHC 1:50-1:200IF 1:100-1:400ICC 1:100-1:400
12kD
Hmga2
P52927,O88791
Rabbit
Polyclonal
Rabbit IgG
Product Information
| Description | HMGA2 rabbit polyclonal |
| Protein full name | High mobility group protein HMGI-C |
Synonyms | High mobility group AT-hook protein 2, LIPO, Hmga2, Hmgic, BABL, STQTL9 |
| Immunogen | Recombinantproteincorrespondingto Mouse HMGA2 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Nucleus |
| Uniprot ID | P52927, O88791 |
Applications
| Applications | IHC，IF |
| Species | Mouse,Rat，Mouse,Rat |
| Dilution | 1:1400-1:2800，1:1400-1:2800 |
| Positive Tissue | liver, spleen, kidney, placenta, colon, brain，brain, heart, testis, stomach |
Background
HMGA2 belongs to the family of high mobility group with AT-hook DNA binding domain. HMGA proteins are considered architectural transcription factors; they do not have direct transcriptional activation capacity, but instead regulate gene expression by changing DNA conformation through binding to AT-rich regions in the DNA and/or direct interaction with other transcription factors . HMGA2 is abundantly and ubiquitously expressed and plays a crucial role during embryonic development. HMGA2 promotes stem cell self-renewal and research studies have shown that decreased HMGA2 expression is associated with stem cell aging. Investigators have shown that expression levels of HMGA2 are very low in normal adult tissues, while either overexpression or rearrangement is associated with many types of cancer.
Images
| Immunohistochemistry analysis of paraffin-embedded mouseliverusing HMGA2 (T611395M) at dilution of 1:1400 |
| Immunohistochemistry analysis of paraffin-embedded mouse spleenusing HMGA2 (T611395M) at dilution of 1:1400 |
| Immunohistochemistry analysis of paraffin-embedded mousekidneyusing HMGA2 (T611395M) at dilution of 1:1400 |
| Immunohistochemistry analysis of paraffin-embedded mouse placenta using HMGA2 (T611395M) at dilution of 1:1400 |
| Immunohistochemistry analysis of paraffin-embedded rat colonusing HMGA2 (T611395M) at dilution of 1:1400 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using HMGA2 (T611395M) at dilution of 1:1400 |
| Immunofluorescentanalysis ofparaformaldehyde-fixedmouse brain using HMGA2 (T611395M) at dilution of 1:1400 |
| Immunofluorescentanalysis ofparaformaldehyde-fixedmouse heart using HMGA2 (T611395M) at dilution of 1:1400 |
| Immunofluorescentanalysis ofparaformaldehyde-fixedmouse testis using HMGA2 (T611395M) at dilution of 1:1400 |
| Immunofluorescentanalysis ofparaformaldehyde-fixedrat stomachusing HMGA2 (T611395M) at dilution of 1:1400 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
Store at +4℃ after thawing. For long-term storage, please store it at -20℃. Avoid repeated freeze / thaw cycles.
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微信客服
邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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